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Campagne de collecte 15 septembre 2024 – 1 octobre 2024

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Articles (57)
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1

Biotechnology in the drug discovery process: Strategic and management issues

Michael Williams, Tony Giordano, Richard A. Elder, H. Joseph Reiser, Gary L. Neil

Journal:

Medicinal Research Reviews

Année:

1993

Langue:

english

Fichier:

PDF, 3.58 MB

english, 1993

2

RNAi: gene-silencing in therapeutic intervention

David J Shuey, Daniel E McCallus, Tony Giordano

Journal:

Drug Discovery Today

Année:

2002

Langue:

english

Fichier:

PDF, 107 KB

english, 2002

3

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

Polhemus, David J., Li, Zhen, Pattillo, Christopher B., Gojon, Gabriel, Gojon, Gabriel, Giordano, Tony, Krum, Henry

Journal:

Cardiovascular Therapeutics

Année:

2015

Langue:

english

Fichier:

PDF, 376 KB

english, 2015

4

Component positioning and ceramic damage in cementless ceramic-on-ceramic total hip arthroplasty

Castagnini, Francesco, Valente, Giordano, Crimi, Gianluigi, Taddei, Fulvia, Bordini, Barbara, Stea, Susanna, Toni, Aldo

Journal:

Journal of Orthopaedic Science

Année:

2019

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2019

5

Computational models to explore the complexity of the epithelial to mesenchymal transition in cancer

Cortesi, Marilisa, Liverani, Chiara, Mercatali, Laura, Ibrahim, Toni, Giordano, Emanuele

Journal:

Wiley Interdisciplinary Reviews: Systems Biology and Medicine

Année:

2020

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2020

6

New development: Managing the Covid-19 pandemicâfrom a hospital-centred model of care to a community co-production approach

Cepiku, Denita, Giordano, Filippo, Bovaird, Tony, Loeffler, Elke

Journal:

Public Money & Management

Année:

2020

Fichier:

PDF, 502 KB

2020

7

Posterior Reversible Encephalopathy Syndrome in infants and young children

Cordelli, Duccio Maria, Marra, Chiara, Ciampoli, Lara, Barbon, Davide, Toni, Francesco, Zama, Daniele, Giordano, Lucio, Milito, Giuseppe, Sartori, Stefano, Sainati, Laura, Foiadelli, Thomas, Mina, Tom

Journal:

European Journal of Paediatric Neurology

Année:

2020

Fichier:

PDF, 872 KB

2020

8

ChemInform Abstract: Design, Synthesis and Characterization of Novel 2-(2,4-Disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one Derivatives as Inhibitors of NF-ϰB and AP-1 Mediated Transcription Activation and as Potential Antiinflammatory Agents.

Rajan S. Giri, Hardik M. Thaker, Tony Giordano, Jill Williams, Donna Rogers, Vasudevan Sudersanam, Kamala K. Vasu

Journal:

Année:

2009

Fichier:

PDF, 25 KB

2009

9

Cloning and sequence of the human α7 nicotinic acetylcholine receptor

Lynn Doucette-Stamm, Lisa M. Monteggia, Diana Donnelly-Roberts, Mei Tai Wang, John Lee, Jingxiang Tian, Tony Giordano

Journal:

Drug Development Research

Année:

1993

Langue:

english

Fichier:

PDF, 472 KB

english, 1993

10

Ganglionic nicotinic acetylcholine receptor activation by the novel agonist ABT-418

Clark A. Briggs, Marion L. Hughes, Lisa M. Monteggia, Tony Giordano, Diana Donnelly-Roberts, Stephen P. Arneric

Journal:

Drug Development Research

Année:

1995

Langue:

english

Fichier:

PDF, 761 KB

english, 1995

11

Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents

Rajan S. Giri, Hardik M. Thaker, Tony Giordano, Jill Williams, Donna Rogers, Vasudevan Sudersanam, Kamala K. Vasu

Journal:

European Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 291 KB

english, 2009

12

Corrigendum to “Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents” [Eur J Med Chem 44 (2009) 2184–2189]

Rajan S. Giri, Hardik M. Thaker, Tony Giordano, Jill Williams, Donna Rogers, Vasudevan Sudersanam, Kamala K. Vasu

Journal:

European Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 78 KB

english, 2009

13

A surrogate-based approach for post-genomic partner identification

Renuka C Pillutla, Ku-chuan Hsiao, Renee Brissette, Paul S Eder, Tony Giordano, Paul W Fletcher, Michael Lennick, Arthur J Blume, Neil I Goldstein

Journal:

BMC Biotechnology

Année:

2001

Langue:

english

Fichier:

PDF, 359 KB

english, 2001

14

Alzheimer’s disease drug discovery targeted to the APP mRNA 5′Untranslated region

Jack T. Rogers, Jeffrey D. Randall, Paul S. Eder, Xudong Huang, Ashley I. Bush, Rudolph E. Tanzi, Amanda Venti, Sandra M. Payton, Tony Giordano, Seiichi Nagano, Catherine M. Cahill, Robert Moir, Debom

Journal:

Journal of Molecular Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 188 KB

english, 2002

15

Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-кB and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer agents

Rajan S. Giri, Hardik M. Thaker, Tony Giordano, Jill Williams, Donna Rogers, Kamala K. Vasu, Vasudevan Sudarsanam

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2010

16

Synthesis and evaluation of quinazolinone derivatives as inhibitors of NF-κB, AP-1 mediated transcription and eIF-4E mediated translational activation: Inhibitors of multi-pathways involve in cancer

Rajan S. Giri, Hardik M. Thaker, Tony Giordano, Bing Chen, Sam Nuthalapaty, Kamala K. Vasu, Vasudevan Sudarsanam

Journal:

European Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 437 KB

english, 2010

17

DELINQUENCY, IDENTITY, AND WOMEN'S INVOLVEMENT IN RELATIONSHIP VIOLENCE

PEGGY C. GIORDANO, TONI J. MILLHOLLIN, STEPHEN A. CERNKOVICH, M. D. PUGH, JENNIFER L. RUDOLPH

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1999

18

The Integrated Role of Desferrioxamine and Phenserine Targeted to an Iron-Responsive Element in the APP-mRNA 5′-Untranslated Region

AMANDA VENTI, TONY GIORDANO, PAUL EDER, ASHLEY I. BUSH, DEBOMOY K. LAHIRI, NIGEL H. GREIG, JACK T. ROGERS

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2004

19

New Therapeutic Strategies and Drug Candidates for Neurodegenerative Diseases: p53 and TNF-α Inhibitors, and GLP-1 Receptor Agonists

NIGEL H. GREIG, MARK P. MATTSON, TRACYANN PERRY, SIC L. CHAN, TONY GIORDANO, KUMAR SAMBAMURTI, JACK T. ROGERS, HAIM OVADIA, DEBOMOY K. LAHIRI

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 42.04 MB

english, 2004

20

Meeting the Needs of Women in Counseling: Implications of a Review of the Literature

Constance A. Hanna, Fred J. Hanna, Francesca G. Giordano, Toni Tollerud

Journal:

The Journal of Humanistic Counseling

Année:

1998

Langue:

english

Fichier:

PDF, 710 KB

english, 1998

21

Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors

Jeffrey M. Carver, P.-Erik Mansson, Luz Cortes-Burgos, Joanne Shu, Li Ming Zhou, James R. Howe, Tony Giordano

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 675 KB

english, 1996

22

Increase in abundance of a transcript hybridizing to elongation factor I alpha during cellular senescence and quiescence

Tony Giordano, Don Kleinsek, Douglas N. Foster

Journal:

Experimental Gerontology

Année:

1989

Langue:

english

Fichier:

PDF, 806 KB

english, 1989

23

Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

Murali Gopalakrishnan, Bruno Buisson, Edward Touma, Tony Giordano, Jeff E. Campbell, Iris C. Hu, Diana Donnelly-Roberts, Stephen P. Arneric, Daniel Bertrand, James P. Sullivan

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 832 KB

english, 1995

24

Inorganic nitrite therapy: historical perspective and future directions

Christopher G. Kevil, Gopi K. Kolluru, Christopher B. Pattillo, Tony Giordano

Journal:

Free Radical Biology and Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 894 KB

english, 2011

25

RNA as a drug target: methods for biophysical characterization and screening

K.Asish Xavier, Paul S Eder, Tony Giordano

Journal:

Trends in Biotechnology

Année:

2000

Langue:

english

Fichier:

PDF, 273 KB

english, 2000

26

Using RNA interference to modulate gene expression

Maninder Chopra, Catherine Pachuk, C Satishchandran, Tony Giordano

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 85 KB

english, 2002

27

Thiothalidomides: Novel Isosteric Analogues of Thalidomide with Enhanced TNF-α Inhibitory Activity†

Giordano, Tony, Yu, Qian-sheng, Holloway, Harold W., Perry, Tracy Ann, Lahiri, Debomoy K., Brossi, Arnold, Greig, Nigel H., Zhu, Xiaoxiang

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 139 KB

english, 2003

28

Similarities between β Amyloid Peptides 1-40 and 40-1: Effects on Aggregation, Toxicity in Vitro, and Injection in Young and Aged Rats

Tony Giordano, Jia Bao Pan, Lisa M. Monteggia, Thomas F. Holzman, Seth W. Snyder, Grant Krafft, Hossein Ghanbari, Neil W. Kowall

Journal:

Experimental Neurology

Année:

1994

Fichier:

PDF, 1.24 MB

1994

29

Hippocampal Injections of Amyloid β-Peptide 1-40 Impair Subsequent One-Trial/Day Reward Learning

David H. Malin, Marie K. Crothers, J.Ronald Lake, Pilar Goyarzu, Robert E. Plotner, Sergio A. Garcia, Stacy H. Spell, Beverly J. Tomsic, Tony Giordano, Neil W. Kowall

Journal:

Neurobiology of Learning and Memory

Année:

2001

Langue:

english

Fichier:

PDF, 281 KB

english, 2001

30

Identification of a highly abundant cDNA isolated from senescent WI-38 cells

Tony Giordano, Douglas N. Foster

Journal:

Experimental Cell Research

Année:

1989

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1989

31

Isolation of a population of transiently transfected quiescent and senescent cells by magnetic affinity cell sorting

Tony Giordano, Tazuko H. Howard, Jerome Coleman, Kazuichi Sakamoto, Bruce H. Howard

Journal:

Experimental Cell Research

Année:

1991

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1991

32

AUUUA-specific mRNA binding proteins in astrocytes

David B. Jacobs, Arthur M. Mandelin II, Tony Giordano, Iris Xue, James S. Malter, Leelabai D. Singh, Ann K. Snyder, Sant P. Singh

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 561 KB

english, 1996

33

Cloning and transient expression of genes encoding the human α4 and β2 neuronal nicotinic acetylcholine receptor (nAChR) subunits

Lisa M. Monteggia, Murali Gopalakrishnan, Edward Touma, Kenneth B. Idler, Norman Nash, Stephen P. Arneric, James P. Sullivan, Tony Giordano

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 425 KB

english, 1995

34

Cloning of the cDNA for the human NMDA receptor NR2C subunit and its expression in the central nervous system and periphery

Yuzhong J. Lin, Sylvie Bovetto, Jeffrey M. Carver, Tony Giordano

Journal:

Molecular Brain Research

Année:

1996

Langue:

english

Fichier:

PDF, 363 KB

english, 1996

35

P1-356 Novel TNF-alpha inhibitors for neurodegeneration: 3-phthalimidoglutarimide analogues

Nigel H. Greig, Tony Giordano, Xiaoxiang Zhu, Qian-Sheng Yu, Harold W. Holloway, Arnold Brossi, Kumar Sambamurti, Debomoy K. Lahiri

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 163 KB

english, 2004

36

MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer

Peng, Hui, Dara, Lily, Li, Tony W.H., Zheng, Yuhua, Yang, Heping, Tomasi, Maria Lauda, Tomasi, Ivan, Giordano, Pasquale, Mato, Jose M., Lu, Shelly C.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.58 MB

english, 2013

37

Nitrite and nitric oxide metabolism in peripheral artery disease

Jason D. Allen, Tony Giordano, Christopher G. Kevil

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 430 KB

english, 2012

38

Expression of Alu and 7SL RNA in Alzheimer's and control brains

Tony Giordano, Steven A. Johnson, Kazuichi Sakamoto, Bruce H. Howard

Journal:

Mechanisms of Ageing and Development

Année:

1992

Langue:

english

Fichier:

PDF, 602 KB

english, 1992

39

Does BRAF V600E Mutation Predict Aggressive Features in Papillary Thyroid Cancer? Results From Four Endocrine Surgery Centers

Li, Carol, Aragon Han, Patricia, Lee, Kathleen C., Lee, Louis C., Fox, Amy C., Beninato, Toni, Thiess, Michele, Dy, Benzon M., Sebo, Thomas J., Thompson, Geoffrey B., Grant, Clive S., Giordano, Thomas

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 119 KB

english, 2013

40

Births, Marriages and Deaths

Chandrasekaran, Krish, Giordano, Tony, Brady, Daniel R., Stoll, James, Martin, Lee J., Rapoport, Stanley I.

Journal:

Année:

1939

Langue:

english

Fichier:

PDF, 376 KB

english, 1939

41

Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease

Chandrasekaran, Krish, Giordano, Tony, Brady, Daniel R., Stoll, James, Martin, Lee J., Rapoport, Stanley I.

Journal:

Molecular Brain Research

Année:

1994

Langue:

english

Fichier:

PDF, 689 KB

english, 1994

42

Altered levels and splicing of the amyloid precursor protein in the adult rat hippocampus after treatment with DMSO or retinoic acid

Pan, Jia Bao, Monteggia, Lisa M., Giordano, Tony

Journal:

Molecular Brain Research

Année:

1993

Langue:

english

Fichier:

PDF, 742 KB

english, 1993

43

Thyroid hormone regulation of NGF, NT-3 and BDNF RNA in the adult rat brain

Giordano, Tony, Pan, Jia Bao, Casuto, Dianne, Watanabe, Shinichi, Arneric, Stephen P.

Journal:

Molecular Brain Research

Année:

1992

Langue:

english

Fichier:

PDF, 644 KB

english, 1992

44

S5-4 Phase I, heart failure clinical trial to evaluate the safety of SG1002 – A novel hydrogen sulfide donor

Gojon, Gabriel, Gojon, Gabriel, Lefer, David J., Elrod, John W., Giordano, Tony

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 51 KB

english, 2014

45

TCT-523 Therapeutic Potential Of Sustained Release Sodium Nitrite For Critical Limb Ischemia In The Setting Of Metabolic Syndrome

Goodchild, Traci T., Polhemus, David J., Bradley, Jessica M., Chang, Carlos C., Islam, Kazi N., Giordano, Tony, Lefer, David J.

Journal:

Journal of the American College of Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 125 KB

english, 2014

46

TCT-434 Vascular Protective Actions Of A Novel Sustained Release Nitrite Formulation In Obese Swine With Metabolic Syndrome

Bradley, Jessica M., Goodchild, Traci T., Polhemus, David J., Chang, Carlos C., Giordano, Tony, Lefer, David J.

Journal:

Journal of the American College of Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 138 KB

english, 2014

47

Single-Dose Pharmacokinetics of Different Oral Sodium Nitrite Formulations in Diabetes Patients

Greenway, Frank L., Predmore, Benjamin L., Flanagan, Douglas R., Giordano, Tony, Qiu, Yang, Brandon, Angela, Lefer, David J., Patel, Rakesh P., Kevil, Christopher G.

Journal:

Diabetes Technology & Therapeutics

Année:

2012

Langue:

english

Fichier:

PDF, 537 KB

english, 2012

48

Clinical evidence of hydrogen sulfide-mediated elevation in circulating nitrite

Polhemus, David J., Elrod, John W., Giordano, Tony, Goodchild, Traci T., Lefer, David J.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 197 KB

english, 2015

49

Utilization of magnetic affinity cell sorting for the isolation of stable transformants

Giordano, Tony, Howard, Tazuko, Howard, Bruce H.

Journal:

Nucleic Acids Research

Année:

1989

Langue:

english

Fichier:

PDF, 64 KB

english, 1989

50

The kendrick extrication device used for pediatric spinal immobilization

Markenson, David, Foltin, George, Tunik, Michael, Cooper, Arthur, Giordano, Lorraine, Fitton, Anne, Lanotte, Toni

Journal:

Prehospital Emergency Care

Année:

1999

Langue:

english

Fichier:

PDF, 609 KB

english, 1999